Cardiovascular diseases Publications

• Refill persistence with chronic medication assessed from a pharmacy database was influenced by method of calculation.Abstract

  BACKGROUND AND OBJECTIVES: In literature, different methods of calculating persistence are used. In this study, the effect of using these different methods on persistence and the association of patients characteristics and persistence are assessed.METHODS: The PHARMO record linkage system was used to calculate persistence with antihypertensive drugs for a cohort of 14,466 new users of antihypertensives

  VanWijk BL, Klungel OH, Heerdink ER, de Boer A. J Clin Epidemiol. 2006 Jan; 59 (1): 11-7.

• Generic substitution of antihypertensive drugs: does it affect adherence?.Abstract

  BACKGROUND: Generic substitution is an important opportunity to reduce the costs of pharmaceutical care. However, pharmacists and physicians often find that patients and brand-name manufacturers have doubt about the equivalence of the substituted dug. This may be reflected by decreased adherence to therapy

  VanWijk BL, Klungel OH, Heerdink ER, de Boer A. Ann Pharmacother. 2006 Jan; 40 (1): 15-20.