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Women's health and paediatrics Publications

Women's health and paediatrics Publications

  • Association between ADHD drug use and injuries among children and adolescents.Abstract

    To study the association between attention deficit hyperactivity disorder (ADHD) drug use and the incidence of hospitalization due to injuries. A random sample of 150,000 persons (0-18 years) was obtained from the Dutch PHARMO record linkage systemAn ADHD medication cohort as well as an up to six age/sex/index date sampled control cohort with no history of ADHD drug use was formed

    van den Ban E, Souverein P, Meijer W, van Engeland H, Swaab H, Egberts T, Heerdink E. Eur Child Adolesc Psychiatry. 2014 Feb; 23 (2): 95-102.
  • Signal detection of potentially drug-induced acute liver injury in children using a multi-country healthcare database network.Abstract

    BACKGROUND: Data mining in spontaneous reporting databases has shown that drug-induced liver injury is infrequently reported in children. OBJECTIVES: Our objectives were to (i) identify drugs potentially associated with acute liver injury (ALI) inhildren and adolescents using electronic healthcare record (EHR) data; and (ii) to evaluate the significance and novelty of these associations

    Ferrajolo C, Coloma PM, Verhamme KM, Schuemie MJ, deBie S, Gini R, Herings R, Mazzaglia G, Picelli G, Giaquinto C, Scotti L, Avillach P, Peder sen L, Rossi F, Capuano A, van der Lei J, Trifiro G, Sturkenboom MC, consortium Eu-Adr. Drug Saf. 2014 Feb; 37 (2): 99-108.
  • The effects of Psychotropic drugs On Developing brain (ePOD) study: methods and design.Abstract

    BACKGROUND: Animal studies have shown that methylphenidate (MPH) and fluoxetine (FLX) have different effects on dopaminergic and serotonergic system in the developing brain compared to the developed brain. The effects of Psychotropic drugs On the Dveloping brain (ePOD) study is a combination of different approaches to determine whether there are related findings in humans

    Bottelier MA, Schouw ML, Klomp A, Tamminga HG, Schrantee AG, Bouziane C, de Ruiter MB, Boer F, Ruhe HG, Denys D, Rijsman R, Lindauer RJ, Reitsma HB, Geurts HM, Reneman L. BMC Psychiatry. 2014 14 48.
  • Disease history and medication use as risk factors for the clinical manifestation of type 1 diabetes in children and young adults: an explorative case control study.Abstract

    BACKGROUND: There is a highly variable asymptomatic period of beta cell destruction prior to the clinical presentation of type1 diabetes. It is not well known what triggers type 1 diabetes to become a clinically overt disease. This explorative studaimed to identify the association between disease history/medication use and the clinical manifestation of type 1 diabetes

    FazeliFarsani S, Souverein PC, van der Vorst MM, Mantel-Teeuwisse AK, Knibbe CA, deBoer A. PLoS One. 2014 9 (2): e87408.
  • Systemic antibiotic prescribing to paediatric outpatients in 5 European countries: a population-based cohort study.Abstract

    BACKGROUND: To describe the utilisation of antibiotics in children and adolescents across 5 European countries based on the same drug utilisation measures and age groups. Special attention was given to age-group-specific distributions of antibioticsubgroups, since comparison in this regard between countries is lacking so far

    Holstiege J, Schink T, Molokhia M, Mazzaglia G, Innocenti F, Oteri A, Bezemer I, Poluzzi E, Puccini A, Ulrichsen SP, Sturkenboom MC, Trifiro G, Garbe E. BMC Pediatr. 2014 14 174.
  • Isotretinoin exposure during pregnancy: a population-based study in The Netherlands.Abstract

    OBJECTIVE: To estimate isotretinoin exposure in Dutch pregnant women despite the implemented pregnancy prevention programme (PPP) and second, to analyse the occurrence of adverse fetal or neonatal outcomes in these isotretinoin exposed pregnancies.DESIGN: Population-based study. SETTING: The Netherlands

    Zomerdijk IM, Ruiter R, Houweling LM, Herings RM, Sturkenboom MC, Straus SM, Stricker BH. BMJ Open. 2014 4 (11): e005602.
  • First year of life medication use and hospital admission rates: premature compared with term infants.Abstract

    OBJECTIVE: To compare hospitalization and medication use during the first year of life in preterm-born and term-born infants. STUDY DESIGN: Data for this retrospective cohort study were obtained from the linked PHARMO-Netherlands Perinatal Registrycohort. From this linked birth cohort, preterm infants (<37 weeks) born between 2004 and 2007 were randomly matched to 4 full-term infants

    Houweling LM, Bezemer ID, Penning-van Beest FJ, Meijer WM, van Lingen RA, Herings RM. J Pediatr. 2013 Jul; 163 (1): 61-6 e1.
  • Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and which study designs do we need to assess safety issues?.Abstract

    BACKGROUND: Data on utilization patterns and safety of non-steroidal anti-inflammatory drugs (NSAIDs) in children are scarce. The purpose of this study was to investigate the utilization of NSAIDs among children in four European countries as part othe Safety Of non-Steroidal anti-inflammatory drugs (SOS) project

    Valkhoff VE, Schade R, tJong GW, Romio S, Schuemie MJ, Arfe A, Garbe E, Herings R, Lucchi S, Picelli G, Schink T, Straatman H, Villa M, Kuipers EJ, Sturkenboom MC, investigatorsofTheSafetyofNon-steroidalAnti-inflammatoryDrugs project. BMC Pediatr. 2013 13 192.
  • Pharmacologic treatment of attention-deficit/hyperactivity disorder in children: incidence, prevalence, and treatment patterns in the Netherlands.Abstract

    BACKGROUND: The prevalence of attention-deficit/hyperactivity disorder (ADHD) and the associated use of stimulant medications may have increased in the Netherlands in recent years, but there is a lack of data to confirm this trend. This retrospectie analysis examined the incidence, prevalence, and treatment pattern of ADHD among children from a large sample representation of the general population of the Netherlands and represents the first such analysis in a large cohort of European children

    Hodgkins P, Sasane R, Meijer WM. Clin Ther. 2011 Feb; 33 (2): 188-203.
  • Treatment stabilization in children and adolescents with attention-deficit/hyperactivity disorder: data from the Netherlands.Abstract

    OBJECTIVE: To evaluate the number of patients reaching stable treatment with a stimulant (methylphenidate or dexamphetamine) or non-stimulant (atomoxetine) attention-deficit/hyperactivity disorder (ADHD) medication approved for use in the Netherlans, and the time to treatment stabilization among children and adolescents aged 6-17 years

    Sasane R, Hodgkins P, Meijer W. Curr Med Res Opin. 2010 Nov; 26 (11): 2565-74.