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Diabetes Publications

Diabetes Publications

  • Change of initial oral antidiabetic therapy in type 2 diabetic patients.Abstract

    Objective To explore the ‘real-life’ therapy of type 2 diabetes mellitus with oral antidiabetic drugs (OADs). Methods From the PHARMO Record Linkage System comprising linked drug dispensing and clinical laboratory data from approximately 2.5 millioindividuals in the Netherlands, among others, new users of OADs were identified in the period 1999-2004

    Plat A, Penning-van Beest F, Kessabi S, Groot M, Herings R. Pharm World Sci. 2009 Dec; 31 (6): 622-6.
  • Large Impact of Antidiabetic Drug Treatment and Hospitalizations on Economic Burden of Diabetes Mellitus in The Netherlands during 2000 to 2004.Abstract

    ABSTRACT Objective: To estimate the burden of diabetes mellitus (DM) and its complications in The Netherlands. Methods: The PHARMO Record Linkage System comprised among others linked drug dispensing, hospital and clinical laboratory data from approimately 2.5 million individuals in The Netherlands. Patients with DM (type 1 and type 2) were included in the study cohort from 2000 to 2004 if they used antidiabetic drugs or had HbA1c >/= 6

    van der Linden MW, Plat AW, Erkens JA, Emneus M, Herings RM. Value Health. 2009 Mar 10; 909-914.
  • Topical corticosteroids and the risk of diabetes mellitus: a nested case-control study in the Netherlands.Abstract

    The relationship between topical corticosteroid use, potency, treatment duration, concomitant exposure to systemic corticosteroids, and risk of diabetes has been incompletely studied. To investigate an association between intense, longstanding topial corticosteroid use and diabetes mellitus. Data for this nested case-control study were obtained from the PHARMO Record Linkage System, including linked drug dispensing and hospital records of >2

    van der Linden MW, Penning-van Beest FJ, Nijsten T, Herings RM. Drug Saf. 2009 32 (6): 527-37.
  • Psoriasis may not be an independent predictor for the use of cardiovascular and anti-diabetic drugs: a 5-year prevalence study.Abstract

    Most studies investigating the association between psoriasis and cardiovascular disease have shown a significant relationship. This comparison study investigated the association between psoriasis and prevalent use of cardiovascular drugs. Drug expoure data for 1998 to 2006 were extracted from the Dutch PHARMO-Record Linkage System database

    Wakkee M, Meijer W, Neumann HA, Herings RM, Nijsten T. Acta Derm Venereol. 2009 89 (5): 476-83.
  • Effect on non-persistent use of oral glucose-lowering drugs on HbA1c goal attainment.Abstract

    Objectives: The aim of this study was to quantify the effect of non-persistence with oral glucose-lowering drugs (OGLD) on HbA1c goal attainment (< 7%) in daily practice.

    Penning-van Beest FJA, van der Bij S, Erkens JA, Kessabi S, Groot M, Herings RM. Curr Med Res Opin. 2008 July; 24 (9): 2523-2529.
  • Differences in the pattern of antibiotic prescription profile and recurrence rate for possible urinary tract infections in women with and without diabetes.Abstract

    OBJECTIVE: Women with diabetes have a high incidence and complication rate of urinary tract infections (UTIs). Our aims were to compare current treatment strategies with respect to recurrence rates in women with diabetes with those without diabetesRESEARCH DESIGN AND METHODS: We used a Dutch registration database containing pharmacy dispensing data

    Schneeberger C, Stolk RP, Devries JH, Schneeberger PM, Herings RM, Geerlings SE. Diabetes Care. 2008 Jul; 31 (7): 1380-5.
  • Influence of antidepressants on glycaemic control in patients with diabetes mellitus.Abstract

    PURPOSE: Anecdotal evidence suggests that antidepressants (ADs) may complicate glycaemic control. The objective of this longitudinal study was to investigate the influence of ADs on glycaemic control within diabetes patients. METHODS: From the pharacy registry database PHARMO, we selected insulin users who did not use oral antidiabetics

    Knol MJ, Derijks HJ, Geerlings MI, Heerdink ER, Souverein PC, Gorter KJ, Grobbee DE, Egberts AC. Pharmacoepidemiol Drug Saf. 2008 Jun; 17 (6): 577-86.
  • The association between antidepressant use and hypoglycaemia in diabetic patients: a nested case-control study.Abstract

    PURPOSE: Hypoglycaemia is a limiting factor for glycaemic management of diabetes with intensive insulin and/or oral antidiabetic drug (OAD) regimen. Case reports suggest that antidepressants may interfere with blood glucose metabolism in patients wth diabetes mellitus potentially increasing the risk of clinically relevant hypoglycaemia

    Derijks HJ, Heerdink ER, DeKoning FH, Janknegt R, Klungel OH, Egberts AC. Pharmacoepidemiol Drug Saf. 2008 Apr; 17 (4): 336-44.
  • Haemoglobin A(1)(c) Goal Attainment in Relation to Dose in Patients with Diabetes Mellitus Taking Metformin : A Nested, Case-Control Study.Abstract

    BACKGROUND and objective: Conclusions from clinical trials suggest possible therapeutic advantages for once-daily agents over twice-daily agents in the treatment of type 2 diabetes mellitus. This study set out to investigate the relationship betweemetformin dosing frequency and glycosylated haemoglobin (HbA(1c))-goal attainment in daily practice

    Penning-van Beest FJ, Wolffenbuttel BH, Herings RM. Clin Drug Investig. 2008 28 (8): 487-493.
  • No increased incidence of diabetes in antidepressant users.Abstract

    This study investigated whether the association between depression and diabetes was influenced by the presence of chronic somatic disease. To distinguish between depression and other psychosocial complaints, we studied the onset of diabetes in antiepressant (AD) users and benzodiazepine (BD) users, respectively

    Knol MJ, Geerlings MI, Egberts AC, Gorter KJ, Grobbee DE, Heerdink ER. Int Clin Psychopharmacol. 2007 Nov; 22 (6): 382-6.