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Diabetes Publications

Diabetes Publications

  • Disease history and medication use as risk factors for the clinical manifestation of type 1 diabetes in children and young adults: an explorative case control study.Abstract

    BACKGROUND: There is a highly variable asymptomatic period of beta cell destruction prior to the clinical presentation of type1 diabetes. It is not well known what triggers type 1 diabetes to become a clinically overt disease. This explorative studaimed to identify the association between disease history/medication use and the clinical manifestation of type 1 diabetes

    FazeliFarsani S, Souverein PC, van der Vorst MM, Mantel-Teeuwisse AK, Knibbe CA, deBoer A. PLoS One. 2014 9 (2): e87408.
  • Risk of fracture with thiazolidinediones: an individual patient data meta-analysis.Abstract

    Background: The use of thiazolidinediones (TZDs) has been associated with increased fracture risks. Our aim was to estimate the risk of fracture with TZDs in three different healthcare registries, using exactly the same study design, and to performan individual patient data meta-analysis of these three studies

    Bazelier MT, de Vries F, Vestergaard P, Herings RM, Gallagher AM, Leufkens HG, van Staa TP. Front Endocrinol (Lausanne). 2013 4 11.
  • Prescribing of rosiglitazone and pioglitazone following safety signals: analysis of trends in dispensing patterns in the Netherlands from 1998 to 2008.Abstract

    BACKGROUND: Relevant safety signals in the EU are regularly communicated in so-called ‘Direct Healthcare Professional Communications’ (DHPCs) or European Medicines Agency (EMA) press releases. Trends of a decrease in the use of rosiglitazone followng regulatory safety warnings have been described in the US

    Ruiter R, Visser LE, van Herk-Sukel MP, Geelhoed-Duijvestijn PH, de Bie S, Straus SM, Mol PG, Romio SA, Herings RM, Stricker BH. Drug Saf. 2012 Jun 1; 35 (6): 471-80.
  • Use of thiazolidinediones and risk of osteoporotic fracture: disease or drugs?.Abstract

    PURPOSE: Clinical and observational studies suggest that use of thiazolidinediones (TZDs) is associated with an increased fracture risk. In addition, type 2 diabetes mellitus (T2DM) is a risk factor for osteoporotic fracture. Our aim was to estimatfracture risks in TZD users and users of other antidiabetic drugs, classified according to proxies of disease severity

    Bazelier MT, Gallagher AM, van Staa TP, Cooper C, Leufkens HG, Vestergaard P, de Vries F. Pharmacoepidemiol Drug Saf. 2012 May; 21 (5): 507-14.
  • Lower risk of cancer in patients on metformin in comparison with those on sulfonylurea derivatives: results from a large population-based follow-up study.Abstract

    OBJECTIVE: Numerous studies have suggested a decreased risk of cancer in patients with diabetes on metformin. Because different comparison groups were used, the effect magnitude is difficult to estimate. Therefore, the objective of this study was tfurther analyze whether, and to what extent, use of metformin is associated with a decreased risk of cancer in a cohort of incident users of metformin compared with users of sulfonylurea derivatives

    Ruiter R, Visser LE, van Herk-Sukel MP, Coebergh JW, Haak HR, Geelhoed-Duijvestijn PH, Straus SM, Herings RM, Stricker BH. Diabetes Care. 2012 Jan; 35 (1): 119-24.
  • Risk of cancer in patients on insulin glargine and other insulin analogues in comparison with those on human insulin: results from a large population-based follow-up study.Abstract

    AIMS/HYPOTHESIS: Several publications suggest an association between certain types of insulin and cancer, but with conflicting results. We investigated whether insulin glargine (A21Gly,B31Arg,B32Arg human insulin) is associated with an increased rik of cancer in a large population-based cohort study

    Ruiter R, Visser LE, van Herk-Sukel MP, Coebergh JW, Haak HR, Geelhoed-Duijvestijn PH, Straus SM, Herings RM, Stricker BH. Diabetologia. 2012 Jan; 55 (1): 51-62.
  • Recurrence of urinary tract infections in postmenopausal diabetic women using different antibiotics.Abstract

    Objectives: Postmenopausal women with diabetes mellitus (DM) have an increased incidence of urinary tract infections (UTI) compared to women without DM. The aim of this study is to compare recurrence rates of UTI in postmenopausal women with DM aftr treatment with nitrofurantoin, the agent of first choice following the Dutch guidelines, with two other common prescribed antibiotics trimethoprim and norfloxacin

    Schneeberger C, Stolk RP, de Vries JH, Herings RMC, Geerlings SE. Journal of Diabetes Mellitus. 2012 2 (2): 261-3.
  • Insulin Glargine versus Insulin Detemir: Glycemic Control and Insulin Dose in Type 2 Diabetes Mellitus Patients Using a Medical Record Linkage System in the Netherlands.Abstract

    Background: In randomized controlled trials, patients with type 2 diabetes mellitus required higher doses of insulin detemir than insulin glargine to obtain the same glycemic control. However, this may differ in daily clinical practice.

    Eland IA, Heintjes EM, Houweling L, de Grooth R, Veneman TF, Bouter KP. J Diabetes Metab. 2011 2 (9): 165.
  • Glycemic control and long-acting insulin analog utilization in patients with type 2 diabetes.Abstract

    INTRODUCTION: The objective was to compare glycemic control, insulin utilization, and body weight in patients with type 2 diabetes (T2D) initiated on insulin detemir (IDet) or insulin glargine (IGlar) in a real-life setting in the Netherlands. METHDS: Insulin-naive patients with T2D, starting treatment with IDet or IGlar between January 1, 2004 and June 30, 2008, were selected from the PHARMO data network

    Heintjes EM, Thomsen TL, Penning-van Beest FJ, Christensen TE, Herings RM. Adv Ther. 2010 Apr; 27 (4): 211-22.
  • Determination of non-treatment with statins of high risk patients in The Netherlands.Abstract

    OBJECTIVE: To determine in the Netherlands what proportions of high risk patients with established cardiovascular disease (CVD) or diabetes mellitus type 2 (DM2) who were not treated with statins on 1 January 2007 and which characteristics were assciated with non-treatment. METHODS: From the IPCI GP database patients were selected who were registered with a GP on 1 January 2007 who had a history of either CVD (CVD patients), DM2 (diabetics) or both (diabetics with CVD)

    van den Haak P, Heintjes E, Plat AW, JanMeerding W, Webb K, Sturkenboom MC, Herings RM. Curr Med Res Opin. 2010 Feb; 26 (2): 271-8.