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Diabetes Publications

Diabetes Publications

  • Cardiovascular medication use and cardiovascular disease in children and adolescents with type 1 diabetes: a population-based cohort study.Abstract

    OBJECTIVES: To investigate the 5-yr prevalence and incidence rates of cardiovascular medication and cardiovascular disease before and after onset of type 1 diabetes (T1D) in children and adolescents. METHODS: Children and adolescents (<19 yr) with1D (n = 925), defined as those who received at least two insulin prescriptions, and a four times larger reference cohort (n = 3591) with the same age and gender in the Dutch PHARMO Record Linkage System (RLS) were studied in a retrospective cohort studybetween 1999 and 2009

    Ahmadizar F, FazeliFarsani S, Souverein PC, van der Vorst MM, deBoer A, Maitland-van der Zee AH. Pediatr Diabetes. 2016 Sep; 17 (6): 433-40.
  • Increasing trends in the incidence and prevalence rates of type 1 diabetes among children and adolescents in the Netherlands.Abstract

    OBJECTIVE: To assess the trends in the incidence and prevalence rates of type 1 diabetes (T1D) among children and adolescents in the Netherlands. METHODS: A population-based cohort study was conducted in the Dutch PHARMO record linkage system (19982011). All children and adolescents aged

    FazeliFarsani S, Souverein PC, van der Vorst MM, Knibbe CA, Herings RM, deBoer A, Mantel-Teeuwisse AK. Pediatr Diabetes. 2016 Feb; 17 (1): 44-52.
  • Identifying Cases of Type 2 Diabetes in Heterogeneous Data Sources: Strategy from the EMIF Project.Abstract

    Due to the heterogeneity of existing European sources of observational healthcare data, data source-tailored choices are needed to execute multi-data source, multi-national epidemiological studies. This makes transparent documentation paramount. Inthis proof-of-concept study, a novel standard data derivation procedure was tested in a set of heterogeneous data sources

    Roberto G, Leal I, Sattar N, Loomis AK, Avillach P, Egger P, van Wijngaarden R, Ansell D, Reisberg S, Tammesoo ML, Alavere H, Pasqua A, Peder sen L, Cunningham J, Tramontan L, Mayer MA, Herings R, Coloma P, Lapi F, Sturkenboom M, van der Lei J, Schuemie MJ, Rijnbeek P, Gini R. PLoS One. 2016 11 (8): e0160648.
  • Pioglitazone use and risk of bladder cancer in patients with type 2 diabetes: retrospective cohort study using datasets from four European countries.Abstract

    OBJECTIVE: To evaluate the association between pioglitazone use and bladder cancer risk in patients with type 2 diabetes. DESIGN: Retrospective cohort study using propensity score matched cohorts. SETTINGS: Healthcare databases from Finland, the Neherlands, Sweden, and the United Kingdom. Data comprised country specific datasets of linked records on prescriptions, hospitals, general practitioners, cancer, and deaths

    Korhonen P, Heintjes EM, Williams R, Hoti F, Christopher S, Majak M, Kool-Houweling L, Strongman H, Linder M, Dolin P, Bahmanyar S. BMJ. 2016 354 i3903.
  • Long term trends in oral antidiabetic drug use among children and adolescents in the Netherlands.Abstract

    AIM: The aim of the study was to document long term trends in oral antidiabetic drug (OAD) use among children and adolescents in the Netherlands. METHODS: A population-based cohort study was conducted using the Dutch PHARMO Database Network. All paients younger than 20 years old with at least one OAD dispensing were identified

    FazeliFarsani S, Souverein PC, Overbeek JA, van der Vorst MM, Knibbe CA, Herings RM, deBoer A, Mantel-Teeuwisse AK. Br J Clin Pharmacol. 2015 Aug; 80 (2): 294-303.
  • Chronic comorbidities in children with type 1 diabetes: a population-based cohort study.Abstract

    OBJECTIVE: To determine the incidence of chronic comorbidities among children with type 1 diabetes (T1D) and to compare incidences with a group of children without diabetes. DESIGN: Population-based cohort study. SETTING: Dutch PHARMO database (199-2010). PATIENTS: All patients (<19 years old) with T1D between 1999 and 2009 (T1D cohort) and a group of age- and sex-matched (ratio: 1-4) children without diabetes (reference cohort)

    FazeliFarsani S, Souverein PC, van der Vorst MM, Knibbe CA, deBoer A, Mantel-Teeuwisse AK. Arch Dis Child. 2015 Aug; 100 (8): 763-8.
  • Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?.Abstract

    BACKGROUND: Metformin, statin and aspirin use seem associated with decreased mortality in cancer patients, though, without adjusting for one another. Independent associations of these drugs with overall mortality after colorectal cancer (CRC) diagnsis within glucose-lowering drugs (GLDs) users were assessed

    Zander s MM, van Herk-Sukel MP, Vissers PA, Herings RM, Haak HR, van dePoll-Franse LV. Br J Cancer. 2015 Jul 28; 113 (3): 403-10.
  • Impact of cancer on adherence to glucose-lowering drug treatment in individuals with diabetes.Abstract

    AIMS/HYPOTHESIS: Adherence to glucose-lowering drug (GLD) treatment regimens is crucial for metabolic control and improving prognosis. Because a diagnosis of cancer might have an impact on adherence to medication, this study explored changes in adhrence to GLDs following a cancer diagnosis. METHODS: All new users of GLDs between 1998 and 2011 who lived in the Eindhoven Cancer Registry-PHARMO Database Network catchment area were selected

    Zander s MM, Haak HR, van Herk-Sukel MP, van dePoll-Franse LV, Johnson JA. Diabetologia. 2015 May; 58 (5): 951-60.
  • High daily insulin exposure in patients with type 2 diabetes is associated with increased risk of cardiovascular events.Abstract

    AIMS: Intensive glucose control, often involving insulin treatment, failed to improve cardiovascular outcomes in several clinical trials. Observational studies reported an association between insulin use and cardiovascular disease (CVD) risk. It hatherefore been suggested that insulin adversely affects CVD risk

    Stoekenbroek RM, Rensing KL, BernelotMoens SJ, Nieuwdorp M, DeVries JH, Zwinder man AH, Stroes ES, Currie CJ, Hutten BA. Atherosclerosis. 2015 Mar 30; 240 (2): 318-323.
  • Population-based cohort study of anti-infective medication use before and after the onset of type 1 diabetes in children and adolescents.Abstract

    A population-based cohort study was conducted in the Dutch PHARMO database to investigate prevalence and patterns of anti-infective medication use in children and adolescents with type 1 diabetes (T1D) before and after the onset of this disease. Alpatients <19 years with at least 2 insulin prescriptions (1999 to 2009) were identified (T1D cohort) and compared with an age- and sex-matched (ratio: 1 up to 4) diabetes-free reference group

    FazeliFarsani S, Souverein PC, van der Vorst MM, Knibbe CA, deBoer A, Mantel-Teeuwisse AK. Antimicrob Agents Chemother. 2014 Aug; 58 (8): 4666-74.