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Diabetes Publications

Diabetes Publications

  • Higher risk of colorectal cancer in patients with newly diagnosed diabetes mellitus before the age of colorectal cancer screening initiation.Abstract

    Type 2 diabetes mellitus (T2DM) is associated with greater risk for colorectal cancer (CRC). The age of onset of T2DM is decreasing worldwide. An increased CRC risk in young T2DM patients could be relevant for the age at which to initiate CRC screeing. We report on CRC risk in T2DM patients with attention to age of diagnosis

    deKort S, Masclee AAM, Sanduleanu S, Weijenberg MP, van Herk-Sukel MPP, Olden hof NJJ, van den Bergh JPW, Haak HR, Janssen-Heijnen ML. Sci Rep. 2017 Apr 24; 7 46527.
  • Impact of detection bias on the risk of gastrointestinal cancer and its subsites in type 2 diabetes mellitus.Abstract

    BACKGROUND: Type 2 diabetes mellitus (T2DM) may be a risk factor for gastrointestinal (GI) cancers, but variations in study designs of observational studies may have yielded biased results due to detection bias. Furthermore, differences in risk forGI cancer subsites have not been extensively evaluated

    deJong RGPJ, Burden AM, deKort S, van Herk-Sukel MPP, Vissers PAJ, Janssen PKC, Haak HR, Masclee AAM, deVries F, Janssen-Heijnen MLG. Eur J Cancer. 2017 Apr 29; 79 61-71.
  • No association between metformin use and survival in patients with pancreatic cancer: An observational cohort study.Abstract

    Several studies have suggested an association between use of metformin and an increased overall survival in patients diagnosed with pancreatic cancer, however with several important methodological limitations. The aim of the study was to assess theassociation between overall survival, pancreatic cancer, and metformin use

    Frouws MA, Mulder BG, Bastiaannet E, Zander s MM, van Herk-Sukel MP, deLeede EM, Bonsing BA, Mieog JS, VandeVelde CJ, Liefers GJ. Medicine (Baltimore). 2017 Mar; 96 (10): e6229.
  • Type 2 Diabetes Mellitus Treatment Patterns Across Europe: A Population-Based Multi-Database Study.Abstract

    PURPOSE: The aim of this study was to determine the similarities and differences of type 2 diabetes mellitus (T2DM) treatment patterns in daily practice in 5 European countries and whether these reflect differences in guidelines. METHODS: Prescriptons for drugs used in diabetes treatment during a 5-year study period were obtained from electronic databases

    Overbeek JA, Heintjes EM, Prieto-Alhambra D, Blin P, Lassalle R, Hall GC, Lapi F, Bianchini E, Hammar N, Bezemer ID, Herings RM. Clin Ther. 2017 Mar 22; 39 759-770.
  • No decreased risk of gastrointestinal cancers in users of metformin in The Netherlands; a time-varying analysis of metformin exposure.Abstract

    Previous studies on metformin use and gastrointestinal (GI) cancer risk have yielded inconclusive results on metformin’s chemoprotective effects. We aimed to evaluate GI cancer risk in users of metformin in The Netherlands using a time-varying apprach in a large population-based database. A cohort study was performed using the NCR-PHARMO database

    deJong RG, Burden AM, deKort S, van Herk-Sukel M, Vissers PA, Janssen PK, Haak HR, Masclee AA, deVries F, Janssen-Heijnen ML. Cancer Prev Res (Phila). 2017 Mar 08;
  • Pioglitazone and risk of mortality in patients with type 2 diabetes: results from a European multidatabase cohort study.Abstract

    OBJECTIVES: Estimate and compare the risk of mortality in patients whose antidiabetic therapy is modified to include pioglitazone compared with an alternative antidiabetic medication at the same stage of disease progression. DESIGN: Retrospective chort study. SETTING: Pooled analysis of clinical data collected from primary and/or secondary care settings in four European countries: Finland, The Netherlands, Sweden and the UK

    Strongman H, Korhonen P, Williams R, Bahmanyar S, Hoti F, Christopher S, Majak M, Kool-Houweling L, Linder M, Dolin P, Heintjes EM. BMJ Open Diabetes Res Care. 2017 5 e000364.
  • Prevalence of diabetes mellitus in the Netherlands more than doubled in the period 1999-2014.Abstract

    OBJECTIVE: To study the trend in the prevalence of diabetes in the Netherlands during the period 1999-2014. DESIGN: Descriptive study of prevalence. METHODS: The prevalence of diabetes during the period 1999-2014 was calculated on the basis of datafrom the PHARMO Database Network, a network of electronic databases that includes data from public pharmacies for 3

    Overbeek JA, van der Heijden AW, Herings RM, Nijpels G. Ned Tijdschr Geneeskd. 2017 161 D673.
  • Glykemische controle met basale insuline in vergelijking met DPP-4-remmers.Abstract

    Achtergrond: Glykemische controle is belangrijk voor de preventie van micro- en macrovasculaire complicaties. De effectiviteit van dipeptidylpeptidase- 4-remmers (DPP-4-remmers) en basale insuline op glykemische controle is onderzocht in gerandomiserde trials. Echter, het effect in de dagelijkse praktijk is vooralsnog onduidelijk

    Kuiper JG, Heintjes EM, Penning-van Beest FJA, Herings RMC. Nederlands Tijdschrift voor Diabetologie. 2017 02 March 2; 15 (1): 5-10.
  • Characterization and cholesterol management in patients with cardiovascular events and/or type 2 diabetes in the Netherlands.Abstract

    OBJECTIVE: To describe clinical characteristics and cholesterol management of patients with cardiovascular events (CVEs) and/or type 2 diabetes mellitus (T2DM) with high low-density lipoprotein cholesterol (LDL-C) > 1.8 mmol/L in the Netherlands. RSEARCH DESIGN AND METHODS: From the PHARMO Database Network a cross-sectional cohort was constructed

    Heintjes E, Kuiper J, Lucius B, Penning-van Beest F, Kutikova L, Liem A, Herings R. Curr Med Res Opin. 2017 Jan; 33 (1): 91-100.
  • Asthma related medication use and exacerbations in children and adolescents with type 1 diabetes.Abstract

    OBJECTIVES: To investigate the use of asthma medication and occurrence of asthma exacerbations up to 5 years before and after the onset of type 1 diabetes mellitus (T1DM) in children and adolescents. METHODS: Children and adolescents younger than 1years with at least 2 insulin prescriptions between 1999 and 2009 classified as T1DM cohort (n = 915) and a 4 times larger reference cohort (n = 3,590) with the same age and gender were identified from the Dutch PHARMO Record Linkage System

    Ahmadizar F, Souverein PC, Arets HG, deBoer A, Maitland-van der Zee AH. Pediatr Pulmonol. 2016 Nov; 51 (11): 1113-1121.