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Rates of prostate surgery and acute urinary retention for benign prostatic hyperplasia in men treated with dutasteride or finasteride

The risk of undergoing BPH-related prostate surgery was lower among men using dutasteride compared to men using finasteride. This was concluded in a study recently published in BMC Urology. In this study, drug dispensing and hospitalisation data from the PHARMO Database Network was used. The majority of dutasteride or finasteride users started treatment in combination with an alpha-blocker. The lower risk of undergoing BPH-related prostate surgery among men using dutasteride was also seen when stratifying by monotherapy or combination therapy, but was only present among men treated by urologists. The number of men admitted for acute urinary retention was too low for comparative analyses.

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