Diabetes Management and Treatment (DIAMANT)
The main aim of the DIAbetes, MANagement and Treatment (DIAMANT) cohort is to gain real-life insights into the treatment and outcomes among people with diabetes in daily general practice in the Netherlands in order to prevent diabetes and its complications.
The DIAMANT cohort is population-based, dynamic, prospective general practitioner (GP) cohort of persons with diabetes. It contains information real world data (RWD) from the electronic GP information systems, which includes structured diagnostic coding systems. The records include information on diagnoses, symptoms, laboratory test results, referrals to specialists and prescriptions and are used in multiple studies. For examples, click the button below.
The cohort is part of the national infrastructure of STIZON and is therefore linked to data from pharmacies, clinical laboratories, Dutch hospitals and to several national registers (e.g. Cancer Registry, Pathology Registry and Perinatal Registry). Linkages to other (not yet linked) data are planned.
This infrastructure enables us to study, manage and support personalised care in order to ultimately improve care and outcomes for people with diabetes.
Facts & figures
- The DIAMANT cohort was established in 2019 and has no fixed time window for in- and exclusion. Effectively, the cohort enables access to information of ~90,000 patients in 2004 to almost 350,000 in 2020 (6% T1D, 84% T2D and for 10% type of diabetes was not recorded), with almost 200,000 participants still registered as being present in 2020.
- Frequency of follow-up of persons with diabetes is GP practice dependent. The Dutch guidelines advise two to four contacts per year with a more extensive yearly check-up. The DIAMANT cohort is updated several times a year.
- Due to the mandatory registration in a GP practice of the Dutch health care system, selection bias in the cohort is minimal.
- The main aim of the DIAMANT cohort is to gain real-life insights into the treatment and outcomes among people with diabetes in daily general practice in order to prevent diabetes and its complications.
- De-identified data from the DIAMANT cohort are available for researchers.
Overbeek JA, van der Heijden AW, Herings RM, Nijpels G. [Prevalence of diabetes mellitus in the Netherlands more than doubled in the period 1999-2014]. Ned Tijdschr Geneeskd 2017; 160: D673.
Overbeek JA, Heintjes EM, Prieto-Alhambra D, et al. Type 2 Diabetes Mellitus Treatment Patterns Across Europe: A Population-based Multi-database Study. Clin Ther 2017; 39(4): 759-70.
Overbeek JA, Kuiper JG, van der Heijden A, et al. Sex- and site-specific differences in colorectal cancer risk among people with type 2 diabetes. Int J Colorectal Dis 2019; 34(2): 269-76.
Overbeek JA, van Herk-Sukel MPP, Vissers PAJ, et al. Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries. Diabetes Care 2019; 42(3): 434-42.